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AACE Clinical Practice Guidelines for Growth Hormone Use in Adults and Children
Developed by The American Association of Clinical Endocrinologists
and The American College of Endocrinology� 1998, AACE
MISSION STATEMENT
The use of growth hormone (GH) in clinical endocrine practice is in an ever-expanding state, and the role of administration of GH in various clinical conditions is becoming increasingly appreciated. Concurrently, increasing use has raised concerns about the ethical and economic issues of GH therapy. Despite public attention and professional interest, no guidelines exist for the use of GH in adults, and the most recent pediatric guidelines were published 3 years ago.
The Board of Directors of the American Association of Clinical Endocrinologists (AACE) believed that a systematic review of recent data and a summary of guidelines for GH use would be timely, useful to clinical endocrinologists, and of interest to both the public and the pharmaceutical companies manufacturing the hormone. Therefore, we have searched for, selected, and synthesized what is known about the safety and efficacy of GH use in clinical practice. Admittedly, some areas of GH application are controversial and will remain so until more data become available.This document consists of recommendations for the clinical use of GH, and it is intended for use by all physicians whose patients may benefit from GH therapy. We recognize that these guidelines are recommendations that should be used by physicians in conjunction with their best clinical judgment. Finally, these guidelines will be revised and updated periodically to reflect the latest developments in GH treatment of endocrine disorders
AACE Clinical Practice Guidelines for Growth Hormone Use in Adults and Children: MISSION STATEMENT (above) INTRODUCTION PHYSIOLOGIC EFFECTS OF GH GH THERAPY IN ADULTS DEFINITION OF ADULT GHD LABORATORY DIAGNOSIS OF GHD TREATMENT OF GHD IN ADULTS GH THERAPY IN CHILDREN GROWTH HORMONE DEFICIENCY TURNER SYNDROME CHRONIC RENAL INSUFFICIENCY INVESTIGATIONAL STUDIES OF GH EFFECTIVENESS SIDE EFFECTS OF GH TREATMENT CONVERSION OF EUROPEAN GH DOSING SPECIFIC GUIDELINES USE ADULTS/CHILDREN CLINICAL PRACTICE OF GH THERAPY ACKNOWLEDGMENT & REFERENCES
Recommended for: Members and Physicians Acrobat Reader Required
GROWTH HORMONE TASK FORCE
CHAIRMEN: Hossein Gharib, M.D., F.A.C.E.
CO-CHAIRMEN: Paul H. Saenger, M.D., F.A.C.E.
Donald Zimmerman, M.D.
COMITTEE Members
H. Jack Baskin, M.D., F.A.C.E.
Bengt-Ake Bengtsson, M.D., PhD
Richard A. Dickey, M.D., F.A.C.E.
Stanley Feld, M.D., M.A.C.E.
Barbara M. Lippe, M.D.
Robert Marcus, M.D.
Todd B. Nippoldt, M.D., F.A.C.E.
Helena W. Rodbard, F.A.C.E.
John A. Seibel, M.D., F.A.C.E.
REVIEWERS
Bruce F. Bower, M.D., F.A.C.E.
Rhoda H. Cobin, M.D., F.A.C.E.
Eugene T. Davidson, M.D., M.A.C.E.
Daniel Einhorn, M.D., F.A.C.E.
Carlos R. Hamilton, Jr., M.D., F.A.C.E.
John J. Janick, M.D., F.A.C.E.
Paul S. Jellinger, M.D., F.A.C.E.
P.J. Palumbo, M.D., F.A.C.E.
Steven M. Petak, M.D., F.A.C.E.
Krisha M. Pinnamaneni, M.D., F.A.C.E.
John B. Tourtelot,, M.D., F.A.C.E.
David A. Westbrock, M.D., F.A.C.E.
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